secobarbital will reduce the extent or effect of aprepitant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.secobarbital will lower the extent or effect of levonorgestrel intrauterine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.secobarbital will minimize the extent or effec